Comprehensive mutational analysis and mRNA isoform quantification ofTP63in normal and neoplastic human prostate cells
نویسندگان
چکیده
منابع مشابه
GSTA1 expression in normal, preneoplastic, and neoplastic human prostate tissue.
BACKGROUND Glutathione S-transferases (GSTs), inducible enzymes that catalyze the detoxification of reactive electrophiles and oxidants, protect against neoplastic transformation. Prostatic adenocarcinoma and high-grade prostatic intraepithelial neoplasia (HGPIN) fail to express GSTP1, a major class of GST. This failure of expression is associated with methlyation of the GSTP1 promoter, a somat...
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ژورنال
عنوان ژورنال: The Prostate
سال: 2009
ISSN: 0270-4137,1097-0045
DOI: 10.1002/pros.20904